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Affiliations: Drs. Winchester, Macfarlane, Thomas, and Price are affiliated with the University of Aberdeen. Financial/nonfinancial disclosures: Dr. Winchester is employed as a medical writer by Oxford PharmaGenesis Ltd. He and Oxford PharmaGenesis have received no industry funding for this research and are undertaking no industry-sponsored projects related to antibiotics or respiratory infection. Dr. Thomas received an honorarium for giving a lecture at an educational meeting arranged by Abbott Laboratories in 2007. Dr. Price is on the independent steering committee of a study looking at the treatment of lower respiratory tract infection in Europe sponsored by Bayer Healthcare; also, he chairs the Research Subcommittee of the International Primary Care Respiratory Group but was not involved in approving this study for funding. Dr. Macfarlane has reported to the ACCP that no significant conflicts of interest exist with any companies/organizations whose products or services may be discussed in this article. Correspondence to: Christopher C. Winchester, DPhil, University of Aberdeen, Department of General Practice and Primary Care, Foresterhill Health Centre, Westburn Rd, Aberdeen AB25 2AY, UK; e-mail: [email protected] © 2009 American College of Chest Physicians. Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (www.chestjournal.org/site/ misc/reprints.xhtml). DOI: 10.1378/chest.09-1449